Entity Details

Primary name NCOA3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO09000
EntryNameNCOA3_MOUSE
FullNameNuclear receptor coactivator 3
TaxID10090
Evidenceevidence at protein level
Length1398
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000993 RNA polymerase II complex binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0010628 positive regulation of gene expression
GO:0016922 nuclear receptor binding
GO:0030307 positive regulation of cell growth
GO:0030331 estrogen receptor binding
GO:0030374 nuclear receptor coactivator activity
GO:0032870 cellular response to hormone stimulus
GO:0032991 protein-containing complex
GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway
GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
GO:0035264 multicellular organism growth
GO:0042975 peroxisome proliferator activated receptor binding
GO:0043066 negative regulation of apoptotic process
GO:0043697 cell dedifferentiation
GO:0044877 protein-containing complex binding
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0047485 protein N-terminus binding
GO:0048471 perinuclear region of cytoplasm
GO:0048589 developmental growth
GO:0050681 androgen receptor binding
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060068 vagina development
GO:0060713 labyrinthine layer morphogenesis
GO:0060744 mammary gland branching involved in thelarche
GO:0071392 cellular response to estradiol stimulus
GO:0072091 regulation of stem cell proliferation
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097718 disordered domain specific binding
GO:1902459 positive regulation of stem cell population maintenance
GO:2000035 regulation of stem cell division
GO:2000036 regulation of stem cell population maintenance
GO:2000737 negative regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR009110 Nuclear receptor coactivator, interlockingFamilyHomologous superfamily
IPR010011 Nuclear receptor coactivator, DUF1518DomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR013767 PAS foldDomainDomain
IPR014920 Nuclear receptor coactivator, Ncoa-type, interlockingDomainDomain
IPR014935 Nuclear receptor coactivator, receptor-binding domainDomainDomain
IPR017426 Nuclear receptor coactivatorFamilyFamily
IPR028818 Nuclear receptor coactivator 3FamilyFamily
IPR032565 Domain of unknown function DUF4927DomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037077 Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamilyFamilyHomologous superfamily

Diseases

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