Entity Details

Primary name FBXW8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BIA4
EntryNameFBXW8_MOUSE
FullNameF-box/WD repeat-containing protein 8
TaxID10090
Evidenceevidence at protein level
Length598
SequenceStatuscomplete
DateCreated2003-10-03
DateModified2021-06-02

Ontological Relatives

GenesFbxw8

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007030 Golgi organization
GO:0008283 cell population proliferation
GO:0016567 protein ubiquitination
GO:0019005 SCF ubiquitin ligase complex
GO:0030687 preribosome, large subunit precursor
GO:0031467 Cul7-RING ubiquitin ligase complex
GO:0048471 perinuclear region of cytoplasm
GO:0050775 positive regulation of dendrite morphogenesis
GO:0060712 spongiotrophoblast layer development
GO:0060716 labyrinthine layer blood vessel development
GO:1901485 positive regulation of transcription factor catabolic process
GO:1990393 3M complex

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR001810 F-box domainDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036047 F-box-like domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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