Entity Details

Primary name SIN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BKH7
EntryNameSIN1_MOUSE
FullNameTarget of rapamycin complex 2 subunit MAPKAP1
TaxID10090
Evidenceevidence at protein level
Length522
SequenceStatuscomplete
DateCreated2008-04-08
DateModified2021-06-02

Ontological Relatives

GenesMapkap1

GO terms

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GOName
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0019901 protein kinase binding
GO:0030950 establishment or maintenance of actin cytoskeleton polarity
GO:0031267 small GTPase binding
GO:0031410 cytoplasmic vesicle
GO:0031932 TORC2 complex
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038203 TORC2 signaling
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0046580 negative regulation of Ras protein signal transduction
GO:0070300 phosphatidic acid binding
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:1900407 regulation of cellular response to oxidative stress

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle
Nucleus

Domains

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DomainNameCategoryType
IPR008828 TORC2 component Sin1/Avo1FamilyFamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR031313 SAPK-interacting protein 1, Pleckstrin-homology domainDomainDomain
IPR031567 Sin1, middle CRIM domainDomainDomain
IPR032679 Sin1, N-terminalDomainDomain

Diseases

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Interactions

4 interactions