Entity Details

Primary name GPER1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BMP4
EntryNameGPER1_MOUSE
FullNameG-protein coupled estrogen receptor 1
TaxID10090
Evidenceevidence at protein level
Length375
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesGper1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001934 positive regulation of protein phosphorylation
GO:0001956 positive regulation of neurotransmitter secretion
GO:0002695 negative regulation of leukocyte activation
GO:0003682 chromatin binding
GO:0003707 steroid hormone receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005496 steroid binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007049 cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007210 serotonin receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010948 negative regulation of cell cycle process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014069 postsynaptic density
GO:0016021 integral component of membrane
GO:0019228 neuronal action potential
GO:0030263 apoptotic chromosome condensation
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change
GO:0030284 estrogen receptor activity
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0030659 cytoplasmic vesicle membrane
GO:0031966 mitochondrial membrane
GO:0032024 positive regulation of insulin secretion
GO:0032591 dendritic spine membrane
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process
GO:0042307 positive regulation of protein import into nucleus
GO:0042311 vasodilation
GO:0042734 presynaptic membrane
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043198 dendritic shaft
GO:0043231 intracellular membrane-bounded organelle
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043401 steroid hormone mediated signaling pathway
GO:0043410 positive regulation of MAPK cascade
GO:0043679 axon terminus
GO:0044327 dendritic spine head
GO:0045087 innate immune response
GO:0045095 keratin filament
GO:0045211 postsynaptic membrane
GO:0045599 negative regulation of fat cell differentiation
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0048786 presynaptic active zone
GO:0050728 negative regulation of inflammatory response
GO:0050769 positive regulation of neurogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0051055 negative regulation of lipid biosynthetic process
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051898 negative regulation of protein kinase B signaling
GO:0055037 recycling endosome
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070474 positive regulation of uterine smooth muscle contraction
GO:0071333 cellular response to glucose stimulus
GO:0071356 cellular response to tumor necrosis factor
GO:0071375 cellular response to peptide hormone stimulus
GO:0071389 cellular response to mineralocorticoid stimulus
GO:0071392 cellular response to estradiol stimulus
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:1900121 negative regulation of receptor binding
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903924 estradiol binding
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1905152 positive regulation of voltage-gated sodium channel activity
GO:1990239 steroid hormone binding
GO:2000353 positive regulation of endothelial cell apoptotic process
GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle membrane
Early endosome
Endoplasmic reticulum membrane
Golgi apparatus
Golgi apparatus membrane
Mitochondrion membrane
Nucleus
Recycling endosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink