Entity Details

Primary name VRK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BN21
EntryNameVRK2_MOUSE
FullNameSerine/threonine-protein kinase VRK2
TaxID10090
Evidenceevidence at protein level
Length503
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesVrk2

GO terms

Show/Hide Table
GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006468 protein phosphorylation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0031966 mitochondrial membrane
GO:0032991 protein-containing complex
GO:0034599 cellular response to oxidative stress
GO:0043408 regulation of MAPK cascade
GO:0046777 protein autophosphorylation
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000659 regulation of interleukin-1-mediated signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Mitochondrion membrane
Nucleus envelope

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
VRK2_MOUSEUBP25_HUMANBioGRID25755282 details
VRK2_MOUSEM3K7_MOUSEBioGRID17709393 details