Entity Details

Primary name KLOT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35082
EntryNameKLOT_MOUSE
FullNameKlotho
TaxID10090
Evidenceevidence at protein level
Length1014
SequenceStatuscomplete
DateCreated2005-10-11
DateModified2021-06-02

Ontological Relatives

GenesKl

GO terms

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GOName
GO:0002526 acute inflammatory response
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0004566 beta-glucuronidase activity
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005975 carbohydrate metabolic process
GO:0006112 energy reserve metabolic process
GO:0007568 aging
GO:0008286 insulin receptor signaling pathway
GO:0008422 beta-glucosidase activity
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0017134 fibroblast growth factor binding
GO:0030501 positive regulation of bone mineralization
GO:0042421 norepinephrine biosynthetic process
GO:0055074 calcium ion homeostasis
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR001360 Glycoside hydrolase family 1FamilyFamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR028546 KlothoFamilyFamily
IPR033132 Glycosyl hydrolases family 1, N-terminal conserved siteSiteConserved site

Diseases

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