Entity Details

Primary name CP27B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO35084
EntryNameCP27B_MOUSE
FullName25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length507
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCyp27b1

GO terms

Show/Hide Table
GOName
GO:0004498 calcidiol 1-monooxygenase activity
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0006816 calcium ion transport
GO:0007568 aging
GO:0008285 negative regulation of cell population proliferation
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
GO:0010980 positive regulation of vitamin D 24-hydroxylase activity
GO:0020037 heme binding
GO:0030282 bone mineralization
GO:0030308 negative regulation of cell growth
GO:0030500 regulation of bone mineralization
GO:0031966 mitochondrial membrane
GO:0032496 response to lipopolysaccharide
GO:0032868 response to insulin
GO:0033280 response to vitamin D
GO:0034341 response to interferon-gamma
GO:0034695 response to prostaglandin E
GO:0036378 calcitriol biosynthetic process from calciol
GO:0042359 vitamin D metabolic process
GO:0042369 vitamin D catabolic process
GO:0042493 response to drug
GO:0043627 response to estrogen
GO:0045618 positive regulation of keratinocyte differentiation
GO:0046688 response to copper ion
GO:0046697 decidualization
GO:0051591 response to cAMP
GO:0055074 calcium ion homeostasis
GO:0062185 secalciferol 1-monooxygenase activity
GO:0070314 G1 to G0 transition
GO:0070564 positive regulation of vitamin D receptor signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Mitochondrion membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002401 Cytochrome P450, E-class, group IFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink