Entity Details

Primary name KMT2C_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BRH4
EntryNameKMT2C_MOUSE
FullNameHistone-lysine N-methyltransferase 2C
TaxID10090
Evidenceevidence at protein level
Length4903
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007338 single fertilization
GO:0010468 regulation of gene expression
GO:0016571 histone methylation
GO:0016746 acyltransferase activity
GO:0035097 histone methyltransferase complex
GO:0035264 multicellular organism growth
GO:0042054 histone methyltransferase activity
GO:0042393 histone binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0044666 MLL3/4 complex
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048146 positive regulation of fibroblast proliferation
GO:0061029 eyelid development in camera-type eye
GO:0097692 histone H3-K4 monomethylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000637 HMG-I/HMG-Y, DNA-binding, conserved siteSiteConserved site
IPR001214 SET domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR003888 FY-rich, N-terminalDomainDomain
IPR003889 FY-rich, C-terminalDomainDomain
IPR009071 High mobility group box domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR034732 Extended PHD (ePHD) domainDomainDomain
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily
IPR037877 Histone-lysine N-methyltransferase 2CFamilyFamily
IPR041967 KMT2C, ePHD1DomainDomain
IPR041968 KMT2C, ePHD2DomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
KMT2C_MOUSENCOA6_MOUSEDIP17021013 details