Entity Details

Primary name VMAT2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BRU6
EntryNameVMAT2_MOUSE
FullNameSynaptic vesicular amine transporter
TaxID10090
Evidenceevidence at protein level
Length517
SequenceStatuscomplete
DateCreated2003-09-19
DateModified2021-06-02

Ontological Relatives

GenesSlc18a2

GO terms

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GOName
GO:0001975 response to amphetamine
GO:0005275 amine transmembrane transporter activity
GO:0005335 serotonin:sodium symporter activity
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006836 neurotransmitter transport
GO:0007568 aging
GO:0007626 locomotory behavior
GO:0008021 synaptic vesicle
GO:0009636 response to toxic substance
GO:0009791 post-embryonic development
GO:0015842 aminergic neurotransmitter loading into synaptic vesicle
GO:0015844 monoamine transport
GO:0016020 membrane
GO:0019899 enzyme binding
GO:0022857 transmembrane transporter activity
GO:0030073 insulin secretion
GO:0030285 integral component of synaptic vesicle membrane
GO:0030672 synaptic vesicle membrane
GO:0031045 dense core granule
GO:0031072 heat shock protein binding
GO:0035690 cellular response to drug
GO:0042593 glucose homeostasis
GO:0042910 xenobiotic transmembrane transporter activity
GO:0042995 cell projection
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0043231 intracellular membrane-bounded organelle
GO:0043679 axon terminus
GO:0044297 cell body
GO:0051589 negative regulation of neurotransmitter transport
GO:0051610 serotonin uptake
GO:0098691 dopaminergic synapse
GO:0098700 neurotransmitter loading into synaptic vesicle
GO:0098794 postsynapse
GO:0098992 neuronal dense core vesicle
GO:0099066 integral component of neuronal dense core vesicle membrane

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR004734 Multidrug resistance proteinFamilyFamily
IPR011701 Major facilitator superfamilyFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01126 DutasterideDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
VMAT2_MOUSESC6A3_MOUSEMINT11343649 details