Entity Details

Primary name ASPH_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BSY0
EntryNameASPH_MOUSE
FullNameAspartyl/asparaginyl beta-hydroxylase
TaxID10090
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesAsph

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0007389 pattern specification process
GO:0008285 negative regulation of cell population proliferation
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0031647 regulation of protein stability
GO:0032237 activation of store-operated calcium channel activity
GO:0032541 cortical endoplasmic reticulum
GO:0033017 sarcoplasmic reticulum membrane
GO:0033198 response to ATP
GO:0035108 limb morphogenesis
GO:0042264 peptidyl-aspartic acid hydroxylation
GO:0045862 positive regulation of proteolysis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0055074 calcium ion homeostasis
GO:0060021 roof of mouth development
GO:0060325 face morphogenesis
GO:0062101 peptidyl-aspartic acid 3-dioxygenase activity
GO:0070588 calcium ion transmembrane transport
GO:0071277 cellular response to calcium ion
GO:0090316 positive regulation of intracellular protein transport
GO:0097202 activation of cysteine-type endopeptidase activity
GO:1901879 regulation of protein depolymerization

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Sarcoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR007803 Aspartyl/asparaginy/proline hydroxylaseDomainDomain
IPR007943 Aspartyl beta-hydroxylase/Triadin domainDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019734 Tetratricopeptide repeatRepeatRepeat
IPR027443 Isopenicillin N synthase-like superfamilyFamilyHomologous superfamily
IPR039038 Aspartyl/asparaginyl beta-hydroxylase familyFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ASPH_MOUSEOTUD4_HUMANBioGRID31138677 details
ASPH_MOUSERAB14_MOUSEIntAct26885862 details