Entity Details

Primary name DNLI4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BTF7
EntryNameDNLI4_MOUSE
FullNameDNA ligase 4
TaxID10090
Evidenceevidence at transcript level
Length911
SequenceStatuscomplete
DateCreated2006-02-07
DateModified2021-06-02

Ontological Relatives

GenesLig4

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000793 condensed chromosome
GO:0001701 in utero embryonic development
GO:0002328 pro-B cell differentiation
GO:0003677 DNA binding
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006260 DNA replication
GO:0006266 DNA ligation
GO:0006281 DNA repair
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0007049 cell cycle
GO:0007417 central nervous system development
GO:0008022 protein C-terminus binding
GO:0008283 cell population proliferation
GO:0010165 response to X-ray
GO:0010212 response to ionizing radiation
GO:0010332 response to gamma radiation
GO:0016874 ligase activity
GO:0032807 DNA ligase IV complex
GO:0033077 T cell differentiation in thymus
GO:0033151 V(D)J recombination
GO:0033152 immunoglobulin V(D)J recombination
GO:0033153 T cell receptor V(D)J recombination
GO:0035019 somatic stem cell population maintenance
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043524 negative regulation of neuron apoptotic process
GO:0045190 isotype switching
GO:0046872 metal ion binding
GO:0048146 positive regulation of fibroblast proliferation
GO:0050769 positive regulation of neurogenesis
GO:0051102 DNA ligation involved in DNA recombination
GO:0051103 DNA ligation involved in DNA repair
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0051402 neuron apoptotic process
GO:0070419 nonhomologous end joining complex
GO:0071285 cellular response to lithium ion
GO:0071479 cellular response to ionizing radiation
GO:0071897 DNA biosynthetic process
GO:0097680 double-strand break repair via classical nonhomologous end joining
GO:2001252 positive regulation of chromosome organization

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000977 DNA ligase, ATP-dependentFamilyFamily
IPR001357 BRCT domainDomainDomain
IPR012308 DNA ligase, ATP-dependent, N-terminalDomainDomain
IPR012309 DNA ligase, ATP-dependent, C-terminalDomainDomain
IPR012310 DNA ligase, ATP-dependent, centralDomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR016059 DNA ligase, ATP-dependent, conserved siteSiteConserved site
IPR021536 DNA ligase IV domainDomainDomain
IPR029710 DNA ligase 4FamilyFamily
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily
IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamilyFamilyHomologous superfamily
IPR044125 DNA Ligase 4, adenylation domainDomainDomain

Diseases

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Interactions

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