Entity Details

Primary name KLK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06870
EntryNameKLK1_HUMAN
FullNameKallikrein-1
TaxID9606
Evidenceevidence at protein level
Length262
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesKLK1

GO terms

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GOName
GO:0003073 regulation of systemic arterial blood pressure
GO:0004252 serine-type endopeptidase activity
GO:0005634 nucleus
GO:0030141 secretory granule
GO:0031638 zymogen activation
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01370 AluminiumDrugbanksmall molecule
DB03127 BenzamidineDrugbanksmall molecule
DB06245 LanoteplaseDrugbankbiotech
DB06692 AprotininDrugbankbiotech
DB06728 AnilineDrugbanksmall molecule
DB12598 NafamostatDrugbanksmall molecule
DB14517 Aluminium phosphateDrugbanksmall molecule
DB14518 Aluminum acetateDrugbanksmall molecule