Entity Details

Primary name CATG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08311
EntryNameCATG_HUMAN
FullNameCathepsin G
TaxID9606
Evidenceevidence at protein level
Length255
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesCTSG

GO terms

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GOName
GO:0002003 angiotensin maturation
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006508 proteolysis
GO:0006955 immune response
GO:0008201 heparin binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0009986 cell surface
GO:0010494 cytoplasmic stress granule
GO:0019221 cytokine-mediated signaling pathway
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0022617 extracellular matrix disassembly
GO:0030141 secretory granule
GO:0033668 negative regulation by symbiont of host apoptotic process
GO:0035578 azurophil granule lumen
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0044267 cellular protein metabolic process
GO:0050778 positive regulation of immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050832 defense response to fungus
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070946 neutrophil-mediated killing of gram-positive bacterium
GO:0071222 cellular response to lipopolysaccharide

Subcellular Location

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Subcellular Location
Cell surface

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02360 Bis-Napthyl Beta-Ketophosphonic AcidDrugbanksmall molecule
DB04016 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic AcidDrugbanksmall molecule