Entity Details

Primary name MCP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15529
EntryNameMCP_HUMAN
FullNameMembrane cofactor protein
TaxID9606
Evidenceevidence at protein level
Length392
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCD46

GO terms

Show/Hide Table
GOName
GO:0001618 virus receptor activity
GO:0002079 inner acrosomal membrane
GO:0002250 adaptive immune response
GO:0002456 T cell mediated immunity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0006958 complement activation, classical pathway
GO:0007338 single fertilization
GO:0008593 regulation of Notch signaling pathway
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0030449 regulation of complement activation
GO:0032733 positive regulation of interleukin-10 production
GO:0035581 sequestering of extracellular ligand from receptor
GO:0038023 signaling receptor activity
GO:0042102 positive regulation of T cell proliferation
GO:0043382 positive regulation of memory T cell differentiation
GO:0045087 innate immune response
GO:0045296 cadherin binding
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0070062 extracellular exosome
GO:0071636 positive regulation of transforming growth factor beta production

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasmic vesicle

Domains

Show/Hide Table
DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR017341 Membrane cofactor protein CD46FamilyFamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table