Entity Details

Primary name FAT4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6V0I7
EntryNameFAT4_HUMAN
FullNameProtocadherin Fat 4
TaxID9606
Evidenceevidence at protein level
Length4981
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesFAT4

GO terms

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GOName
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0003007 heart morphogenesis
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0007009 plasma membrane organization
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007219 Notch signaling pathway
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016021 integral component of membrane
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0035329 hippo signaling
GO:0043931 ossification involved in bone maturation
GO:0045177 apical part of cell
GO:0048565 digestive tract development
GO:0060122 inner ear receptor cell stereocilium organization
GO:0070062 extracellular exosome
GO:0072137 condensed mesenchymal cell proliferation
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR020894 Cadherin conserved siteSiteConserved site

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FAT4_HUMANATX1_HUMANBioGRID, HPRD, IntAct16713569 details
FAT4_HUMANTNKS2_HUMANIntAct22153077 details
FAT4_HUMANUBP51_HUMANBioGRID31217854 details