Entity Details

Primary name GDF7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z4P5
EntryNameGDF7_HUMAN
FullNameGrowth/differentiation factor 7
TaxID9606
Evidenceevidence at transcript level
Length450
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesGDF7

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0007411 axon guidance
GO:0008083 growth factor activity
GO:0010628 positive regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021509 roof plate formation
GO:0021527 spinal cord association neuron differentiation
GO:0022612 gland morphogenesis
GO:0030509 BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0030901 midbrain development
GO:0032924 activin receptor signaling pathway
GO:0042802 identical protein binding
GO:0045165 cell fate commitment
GO:0045666 positive regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048608 reproductive structure development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048853 forebrain morphogenesis
GO:0060389 pathway-restricted SMAD protein phosphorylation
GO:0060395 SMAD protein signal transduction
GO:0060571 morphogenesis of an epithelial fold
GO:2001051 positive regulation of tendon cell differentiation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GDF7_HUMANBMP7_HUMANHPRD12741987 details