Entity Details

Primary name NR5A2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00482
EntryNameNR5A2_HUMAN
FullNameNuclear receptor subfamily 5 group A member 2
TaxID9606
Evidenceevidence at protein level
Length541
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesNR5A2

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008206 bile acid metabolic process
GO:0008270 zinc ion binding
GO:0009755 hormone-mediated signaling pathway
GO:0009792 embryo development ending in birth or egg hatching
GO:0009888 tissue development
GO:0030855 epithelial cell differentiation
GO:0042127 regulation of cell population proliferation
GO:0042592 homeostatic process
GO:0042632 cholesterol homeostasis
GO:0043565 sequence-specific DNA binding
GO:0045070 positive regulation of viral genome replication
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061113 pancreas morphogenesis
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097720 calcineurin-mediated signaling
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR016355 Nuclear hormone receptor family 5FamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
NR5A2_HUMANEDF1_HUMANBioGRID, HPRD, IntAct12040021 details
NR5A2_HUMANUBC9_HUMANBioGRID, MINT17036045 19692572 details
NR5A2_HUMANPROX1_HUMANbhf-ucl, HPRD15205472 16488887 details
NR5A2_HUMANT2H2L_HUMANBioGRID, IntAct32296183 details
NR5A2_HUMANCTNB1_HUMANDIP22187462 details
NR5A2_HUMANNR0B2_HUMANBioGRID, DIP, HPRD11668176 12198243 14963109 20375098 20516075 21262773 21566081 22504882 details
NR5A2_HUMANNCOR2_HUMANDIP22504882 details
NR5A2_HUMANPRGC1_HUMANBioGRID, DIP17283069 20133449 22504882 details
NR5A2_HUMANNCOA2_HUMANDIP22504882 details
NR5A2_HUMANNCOA1_HUMANBioGRID, DIP15604093 22504882 23975195 details
NR5A2_HUMANNCOA3_HUMANBioGRID11668176 details
NR5A2_HUMANALBU_HUMANBioGRID, HPRD15604093 details
NR5A2_HUMANFRIH_HUMANBioGRID15604093 details
NR5A2_HUMANNRIP1_HUMANBioGRID, HPRD15604093 details
NR5A2_HUMANBCKD_HUMANBioGRID15604093 details
NR5A2_HUMANANF_HUMANBioGRID, HPRD15604093 details
NR5A2_HUMANPNRC1_HUMANBioGRID, HPRD15604093 details
NR5A2_HUMANPNRC2_HUMANBioGRID, HPRD15604093 details
NR5A2_HUMANARIP4_HUMANBioGRID19692572 details
NR5A2_HUMANCREB1_HUMANBioGRID18191017 details
NR5A2_HUMANNSD1_HUMANBioGRID23975195 details
NR5A2_HUMANNR1I2_HUMANBioGRID15331348 details
NR5A2_HUMANDDB2_HUMANBioGRID30923324 details
NR5A2_HUMANSRBP2_HUMANBioGRID17283069 details
NR5A2_HUMANSRBP1_HUMANBioGRID17283069 details
NR5A2_HUMANRPB4_HUMANHPRD15604093 details
NR5A2_HUMANILF3_HUMANBioGRID21554248 details
NR5A2_HUMANGPS2_HUMANBioGRID17895379 details
NR5A2_HUMANSMRD3_HUMANHPRD14701856 details