Entity Details

Primary name PLPP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14494
EntryNamePLPP1_HUMAN
FullNamePhospholipid phosphatase 1
TaxID9606
Evidenceevidence at protein level
Length284
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesPLPP1

GO terms

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GOName
GO:0000810 diacylglycerol diphosphate phosphatase activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0006644 phospholipid metabolic process
GO:0006670 sphingosine metabolic process
GO:0006672 ceramide metabolic process
GO:0007165 signal transduction
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0008195 phosphatidate phosphatase activity
GO:0008285 negative regulation of cell population proliferation
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019216 regulation of lipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0042392 sphingosine-1-phosphate phosphatase activity
GO:0042577 lipid phosphatase activity
GO:0045121 membrane raft
GO:0046839 phospholipid dephosphorylation
GO:0070062 extracellular exosome
GO:0106235 ceramide-1-phosphate phosphatase activity

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidaseDomainDomain
IPR028670 Lipid phosphate phosphohydrolase 1FamilyFamily
IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamilyFamilyHomologous superfamily
IPR043216 Phospholipid phosphataseFamilyFamily

Diseases

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