| Domain | Name | Category | Type |
| IPR004520 | tRNA modification GTPase MnmE | Family | Family |
| IPR005225 | Small GTP-binding protein domain | Domain | Domain |
| IPR006073 | GTP binding domain | Domain | Domain |
| IPR018948 | GTP-binding protein TrmE, N-terminal | Domain | Domain |
| IPR025867 | MnmE, helical domain | Domain | Domain |
| IPR027266 | GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 | Family | Homologous superfamily |
| IPR027368 | tRNA modification GTPase MnmE domain 2 | Family | Homologous superfamily |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Family | Homologous superfamily |
| IPR031168 | TrmE-type guanine nucleotide-binding domain | Domain | Domain |