Entity Details

Primary name AIM2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14862
EntryNameAIM2_HUMAN
FullNameInterferon-inducible protein AIM2
TaxID9606
Evidenceevidence at protein level
Length343
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesAIM2

GO terms

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GOName
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0003690 double-stranded DNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032731 positive regulation of interleukin-1 beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035458 cellular response to interferon-beta
GO:0035690 cellular response to drug
GO:0042802 identical protein binding
GO:0044546 NLRP3 inflammasome complex assembly
GO:0045087 innate immune response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070269 pyroptosis
GO:0097169 AIM2 inflammasome complex
GO:1904270 pyroptosome complex assembly
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004020 DAPIN domainDomainDomain
IPR004021 HIN-200/IF120xDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR040205 HIN-200 familyFamilyFamily

Diseases

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