Entity Details

Primary name GNL3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BVP2
EntryNameGNL3_HUMAN
FullNameGuanine nucleotide-binding protein-like 3
TaxID9606
Evidenceevidence at protein level
Length549
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesGNL3

GO terms

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GOName
GO:0003723 RNA binding
GO:0005525 GTP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0008283 cell population proliferation
GO:0016020 membrane
GO:0016604 nuclear body
GO:0017145 stem cell division
GO:0019827 stem cell population maintenance
GO:0030496 midbody
GO:0032206 positive regulation of telomere maintenance
GO:0033235 positive regulation of protein sumoylation
GO:0042127 regulation of cell population proliferation
GO:0048027 mRNA 5'-UTR binding
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904816 positive regulation of protein localization to chromosome, telomeric region

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006073 GTP binding domainDomainDomain
IPR014813 Guanine nucleotide-binding protein-like 3, N-terminal domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domainDomainDomain

Diseases

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Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
GNL3_HUMAN2A5A_HUMANHPRD, IntAct16097049 details
GNL3_HUMANP53_HUMANBioGRID, HPRD, IntAct12464630 19033382 details
GNL3_HUMANASCC2_HUMANBioGRID, HPRD, IntAct16169070 details
GNL3_HUMANMDM2_HUMANBioGRID, I2D18426907 19033382 21132010 24769896 details
GNL3_HUMANSTAT3_HUMANBioGRID, IntAct21988832 details
GNL3_HUMANDYSF_HUMANBioGRID, IntAct23414517 details
GNL3_HUMANNPM_HUMANBioGRID, IntAct18448670 26496610 details
GNL3_HUMANCEP19_HUMANBioGRID, IntAct26638075 32296183 details
GNL3_HUMANCDN2A_HUMANBioGRID24769896 details
GNL3_HUMANARF_HUMANBioGRID24769896 details
GNL3_HUMANCDN1B_HUMANBioGRID27998760 details
GNL3_HUMANPTEN_HUMANBioGRID31685992 details
GNL3_HUMANING4_HUMANBioGRID31754246 details
GNL3_HUMANOGT1_HUMANBioGRID32994395 details
GNL3_HUMANWRP73_HUMANIntAct17353931 details
GNL3_HUMANMYC_HUMANBioGRID, IntAct17353931 29467282 30415952 details
GNL3_HUMANSPF30_HUMANIntAct17353931 details
GNL3_HUMANPHLA3_HUMANIntAct17353931 details
GNL3_HUMANLYAR_HUMANIntAct17353931 details
GNL3_HUMANCIAO1_HUMANIntAct17353931 details
GNL3_HUMANPPIP1_HUMANIntAct17353931 details
GNL3_HUMANAGO2_HUMANMINT17932509 24550003 details
GNL3_HUMANNR2F6_HUMANIntAct20195357 details
GNL3_HUMANTERT_HUMANMINT24550003 details
GNL3_HUMANNOP56_HUMANBioGRID, IntAct12777385 22939629 26344197 26496610 34079125 details
GNL3_HUMANBIN1_HUMANIntAct31413325 details
GNL3_HUMANDOT1L_HUMANBioGRID20431927 details
GNL3_HUMANTERF1_HUMANBioGRID17000763 19487455 details
GNL3_HUMAN3MG_HUMANBioGRID23537643 details
GNL3_HUMANTRIPC_HUMANBioGRID24769896 details
GNL3_HUMANUB2R1_HUMANBioGRID29564676 details
GNL3_HUMANM3K13_HUMANBioGRID31186535 details
GNL3_HUMANISG15_HUMANBioGRID33024031 details