Entity Details

Primary name LOXL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4K0
EntryNameLOXL2_HUMAN
FullNameLysyl oxidase homolog 2
TaxID9606
Evidenceevidence at protein level
Length774
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesLOXL2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0001666 response to hypoxia
GO:0001837 epithelial to mesenchymal transition
GO:0001935 endothelial cell proliferation
GO:0002040 sprouting angiogenesis
GO:0004720 protein-lysine 6-oxidase activity
GO:0005044 scavenger receptor activity
GO:0005507 copper ion binding
GO:0005509 calcium ion binding
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0006464 cellular protein modification process
GO:0007155 cell adhesion
GO:0007568 aging
GO:0009055 electron transfer activity
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0016020 membrane
GO:0018057 peptidyl-lysine oxidation
GO:0030199 collagen fibril organization
GO:0032332 positive regulation of chondrocyte differentiation
GO:0043542 endothelial cell migration
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046688 response to copper ion
GO:0062023 collagen-containing extracellular matrix
GO:0070492 oligosaccharide binding
GO:0070828 heterochromatin organization
GO:1902455 negative regulation of stem cell population maintenance

Subcellular Location

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Subcellular Location
Chromosome
Endoplasmic reticulum
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR001190 SRCR domainDomainDomain
IPR001695 Lysyl oxidaseFamilyFamily
IPR017448 SRCR-like domainDomainDomain
IPR019828 Lysyl oxidase, conserved siteSiteConserved site
IPR036772 SRCR-like domain superfamilyFamilyHomologous superfamily

Diseases

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