Entity Details

Primary name KLK8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60259
EntryNameKLK8_HUMAN
FullNameKallikrein-8
TaxID9606
Evidenceevidence at protein level
Length260
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesKLK8

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007613 memory
GO:0008219 cell death
GO:0009611 response to wounding
GO:0030141 secretory granule
GO:0031642 negative regulation of myelination
GO:0043616 keratinocyte proliferation
GO:0048681 negative regulation of axon regeneration
GO:0048812 neuron projection morphogenesis
GO:0050807 regulation of synapse organization
GO:0050808 synapse organization
GO:0097180 serine protease inhibitor complex

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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