Entity Details

Primary name IF4E2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60573
EntryNameIF4E2_HUMAN
FullNameEukaryotic translation initiation factor 4E type 2
TaxID9606
Evidenceevidence at protein level
Length245
SequenceStatuscomplete
DateCreated2003-04-11
DateModified2021-06-02

Ontological Relatives

GenesEIF4E2

GO terms

Show/Hide Table
GOName
GO:0000339 RNA cap binding
GO:0000340 RNA 7-methylguanosine cap binding
GO:0000932 P-body
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005845 mRNA cap binding complex
GO:0008135 translation factor activity, RNA binding
GO:0016281 eukaryotic translation initiation factor 4F complex
GO:0017148 negative regulation of translation
GO:0031047 gene silencing by RNA
GO:0031625 ubiquitin protein ligase binding
GO:1905618 positive regulation of miRNA mediated inhibition of translation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR001040 Translation Initiation factor eIF- 4eFamilyFamily
IPR019770 Eukaryotic translation initiation factor 4E (eIF-4E), conserved siteSiteConserved site
IPR023398 Translation Initiation factor eIF- 4e-likeFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

131 interactions

InteractorPartnerSourcesPublicationsLink
IF4E2_HUMAN4EBP1_HUMANBioGRID, HPRD, IntAct15094042 32296183 details
IF4E2_HUMAN4ET_HUMANBioGRID, HPRD, IntAct16189514 19060904 22751931 28514442 32296183 details
IF4E2_HUMAN4EBP3_HUMANBioGRID, HPRD, IntAct16189514 details
IF4E2_HUMANK1C20_HUMANBioGRID, HPRD, IntAct16189514 details
IF4E2_HUMANKR412_HUMANBioGRID, HPRD, IntAct16189514 details
IF4E2_HUMANMDFI_HUMANBioGRID, IntAct19060904 details
IF4E2_HUMANNECA2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANSPY2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANTAD2A_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANK1C19_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANTRI27_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANMYOG_HUMANBioGRID, IntAct25416956 31515488 details
IF4E2_HUMANITF2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANKR105_HUMANIntAct25416956 details
IF4E2_HUMANKR108_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANKR109_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANCDR2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANREL_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANTLE5_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANK1H1_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANUBX11_HUMANBioGRID, IntAct21516116 25416956 details
IF4E2_HUMANK1C40_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANATL4_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANUBP54_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANNT2NA_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANHOMEZ_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANUSBP1_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANCBY2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANMIPO1_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANZBTB9_HUMANBioGRID, IntAct25416956 31515488 details
IF4E2_HUMANSPAG5_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANLZTS2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANTRI54_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANPRD14_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANCARD9_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANMARE3_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANAMOL2_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANMAGD1_HUMANBioGRID, IntAct25416956 details
IF4E2_HUMANGGYF2_HUMANBioGRID, IntAct22751931 24981860 27173435 28514442 30917308 unassigned1312 details
IF4E2_HUMANHD_HUMANBioGRID, IntAct, UniProt25959826 32814053 details
IF4E2_HUMANARI1_HUMANBioGRID, HPRD14623119 details
IF4E2_HUMANA4_HUMANBioGRID21832049 details
IF4E2_HUMANFBX25_HUMANBioGRID23940030 details
IF4E2_HUMANK1C13_HUMANBioGRID25416956 details
IF4E2_HUMANTMCC2_HUMANBioGRID25416956 details
IF4E2_HUMANNT2NC_HUMANBioGRID25416956 details
IF4E2_HUMANMGT5B_HUMANBioGRID32296183 details
IF4E2_HUMAN1433Z_HUMANMINT15161933 details
IF4E2_HUMANDCLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANCHK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSI1L1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANKIF1C_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMAST3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANKIF1B_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANEDC3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANKSR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMYCPP_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSRGP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANGGYF1_HUMANIntAct28514442 unassigned1312 details
IF4E2_HUMANNADK_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANNF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMPIP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMPIP3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANAFAD_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANHDAC4_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANCDK16_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPTN13_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANCAMP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANTIAM1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMELK_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANZN638_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPTN14_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANTBC25_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANM3K21_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSPD2A_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANDEN4C_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANAN34A_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPKHA7_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANLARP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSYDE1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPHLB2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANRGPS2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANRPTOR_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANNAV1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANF110B_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANHDAC7_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSH3R3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANDEN1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANDEP1B_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSRS12_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANRAB3I_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANMAGI1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANTESK2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSIN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANF110A_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANLPIN3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANRTKN_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANOSBL6_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPKHA5_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANTANC2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANINP5E_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANFA53C_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSH3B4_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANLIMA1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANNGAP_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANUBP21_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANPPM1H_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANAGAP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANGAB2_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANSTA13_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
IF4E2_HUMANEPAS1_HUMANDIP22678294 details
IF4E2_HUMANUB2L3_HUMANBioGRID14623119 details
IF4E2_HUMAN1433E_HUMANBioGRID17979178 details
IF4E2_HUMANZN598_HUMANBioGRID22751931 28685749 details
IF4E2_HUMANZ3H7A_HUMANBioGRID29395067 30995489 details
IF4E2_HUMANMEX3B_HUMANBioGRID29395067 details
IF4E2_HUMANRN214_HUMANBioGRID29395067 details
IF4E2_HUMANTNR6A_HUMANBioGRID29395067 details
IF4E2_HUMANTNR6B_HUMANBioGRID29395067 details
IF4E2_HUMANUBP2L_HUMANBioGRID29395067 details
IF4E2_HUMANYTHD2_HUMANBioGRID29395067 details
IF4E2_HUMANTTP_HUMANBioGRID29395067 details
IF4E2_HUMANCNOT2_HUMANBioGRID29395067 details
IF4E2_HUMANPRC2A_HUMANBioGRID29395067 details
IF4E2_HUMANTNR6C_HUMANBioGRID29395067 details