Entity Details

Primary name S22A5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO76082
EntryNameS22A5_HUMAN
FullNameSolute carrier family 22 member 5
TaxID9606
Evidenceevidence at protein level
Length557
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSLC22A5

GO terms

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GOName
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006814 sodium ion transport
GO:0009609 response to symbiotic bacterium
GO:0015226 carnitine transmembrane transporter activity
GO:0015293 symporter activity
GO:0015651 quaternary ammonium group transmembrane transporter activity
GO:0015697 quaternary ammonium group transport
GO:0015879 carnitine transport
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030165 PDZ domain binding
GO:0031526 brush border membrane
GO:0042910 xenobiotic transmembrane transporter activity
GO:0060731 positive regulation of intestinal epithelial structure maintenance
GO:0070062 extracellular exosome
GO:0070715 sodium-dependent organic cation transport
GO:0150104 transport across blood-brain barrier
GO:1901235 (R)-carnitine transmembrane transporter activity
GO:1902270 (R)-carnitine transmembrane transport
GO:1902603 carnitine transmembrane transport
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR004749 Organic cation transport protein/SVOPFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR005829 Sugar transporter, conserved siteSiteConserved site
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00122 CholineDrugbanksmall molecule
DB00125 ArginineDrugbanksmall molecule
DB00148 CreatineDrugbanksmall molecule
DB00152 ThiamineDrugbanksmall molecule
DB00182 AmphetamineDrugbanksmall molecule
DB00184 NicotineDrugbanksmall molecule
DB00281 LidocaineDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00332 IpratropiumDrugbanksmall molecule
DB00345 Aminohippuric acidSwissprotsmall molecule
DB00365 GrepafloxacinDrugbanksmall molecule
DB00368 NorepinephrineDrugbanksmall molecule
DB00415 AmpicillinDrugbanksmall molecule
DB00438 CeftazidimeDrugbanksmall molecule
DB00456 CefalotinDrugbanksmall molecule
DB00468 QuinineDrugbanksmall molecule
DB00501 CimetidineDrugbanksmall molecule
DB00535 CefdinirDrugbanksmall molecule
DB00536 GuanidineDrugbanksmall molecule
DB00567 CephalexinDrugbanksmall molecule
DB00575 ClonidineDrugbanksmall molecule
DB00583 LevocarnitineDrugbanksmall molecule
DB00627 NiacinDrugbanksmall molecule
DB00661 VerapamilDrugbanksmall molecule
DB00671 CefiximeDrugbanksmall molecule
DB00689 CephaloglycinDrugbanksmall molecule
DB00695 FurosemideDrugbanksmall molecule
DB00908 QuinidineDrugbanksmall molecule
DB00970 DactinomycinDrugbanksmall molecule
DB00978 LomefloxacinDrugbanksmall molecule
DB00983 FormoterolDrugbanksmall molecule
DB00988 DopamineDrugbanksmall molecule
DB01000 CyclacillinDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB01035 ProcainamideDrugbanksmall molecule
DB01053 BenzylpenicillinDrugbanksmall molecule
DB01059 NorfloxacinDrugbanksmall molecule
DB01075 DiphenhydramineDrugbanksmall molecule
DB01140 CefadroxilDrugbanksmall molecule
DB01151 DesipramineDrugbanksmall molecule
DB01165 OfloxacinDrugbanksmall molecule
DB01208 SparfloxacinDrugbanksmall molecule
DB01333 CefradineDrugbanksmall molecule
DB01409 TiotropiumDrugbanksmall molecule
DB01413 CefepimeDrugbanksmall molecule
DB01577 MetamfetamineDrugbanksmall molecule
DB03128 AcetylcholineDrugbanksmall molecule
DB04133 Degraded CephaloridineDrugbanksmall molecule
DB04630 AldosteroneDrugbanksmall molecule
DB05381 HistamineDrugbanksmall molecule
DB06691 MepyramineDrugbanksmall molecule
DB08795 AzidocillinDrugbanksmall molecule
DB08837 TetraethylammoniumDrugbanksmall molecule
DB08842 AcetylcarnitineSwissprotsmall molecule
DB09237 LevamlodipineDrugbanksmall molecule
DB14006 Choline salicylateDrugbanksmall molecule
DB14754 SolriamfetolDrugbanksmall molecule