Entity Details

Primary name EPO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01588
EntryNameEPO_HUMAN
FullNameErythropoietin
TaxID9606
Evidenceevidence at protein level
Length193
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesEPO

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005125 cytokine activity
GO:0005128 erythropoietin receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006915 apoptotic process
GO:0006953 acute-phase response
GO:0007165 signal transduction
GO:0007566 embryo implantation
GO:0007568 aging
GO:0008015 blood circulation
GO:0008284 positive regulation of cell population proliferation
GO:0009651 response to salt stress
GO:0009986 cell surface
GO:0010523 negative regulation of calcium ion transport into cytosol
GO:0010976 positive regulation of neuron projection development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0018105 peptidyl-serine phosphorylation
GO:0030218 erythrocyte differentiation
GO:0030295 protein kinase activator activity
GO:0032496 response to lipopolysaccharide
GO:0033189 response to vitamin A
GO:0033574 response to testosterone
GO:0038162 erythropoietin-mediated signaling pathway
GO:0042104 positive regulation of activated T cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042541 hemoglobin biosynthetic process
GO:0043249 erythrocyte maturation
GO:0043627 response to estrogen
GO:0044297 cell body
GO:0045666 positive regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046579 positive regulation of Ras protein signal transduction
GO:0048678 response to axon injury
GO:0051602 response to electrical stimulus
GO:0055093 response to hyperoxia
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0071474 cellular hyperosmotic response
GO:0071548 response to dexamethasone
GO:1901215 negative regulation of neuron death
GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
GO:1902251 negative regulation of erythrocyte apoptotic process
GO:2001258 negative regulation of cation channel activity

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001323 Erythropoietin/thrombopoietinFamilyFamily
IPR003013 ErythropoietinFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR019767 Erythropoietin/thrombopoeitin, conserved siteSiteConserved site

Diseases

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