Entity Details

Primary name CSF2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15509
EntryNameCSF2R_HUMAN
FullNameGranulocyte-macrophage colony-stimulating factor receptor subunit alpha
TaxID9606
Evidenceevidence at protein level
Length400
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCSF2RA

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0004896 cytokine receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0038023 signaling receptor activity
GO:0043235 receptor complex
GO:0044267 cellular protein metabolic process

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003532 Short hematopoietin receptor, family 2, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015321 Type I cytokine receptor, cytokine-binding domainDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR040907 IL-3 receptor alpha chain, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00020 SargramostimDrugbankbiotech
DB05194 KB002Drugbanksmall molecule
DB05386 RegramostimDrugbankbiotech
DB10770 Foreskin fibroblast (neonatal)Drugbankbiotech
DB10772 Foreskin keratinocyte (neonatal)Drugbankbiotech
DB11338 Clove oilDrugbankbiotech