Entity Details

Primary name TRY3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35030
EntryNameTRY3_HUMAN
FullNameTrypsin-3
TaxID9606
Evidenceevidence at protein level
Length304
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesPRSS3

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0007586 digestion
GO:0008236 serine-type peptidase activity
GO:0009235 cobalamin metabolic process
GO:0019730 antimicrobial humoral response
GO:0031638 zymogen activation
GO:0043312 neutrophil degranulation
GO:0043542 endothelial cell migration
GO:1904724 tertiary granule lumen

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02308 4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-AminiumDrugbanksmall molecule
DB02541 4-Hydroxybutan-1-AminiumDrugbanksmall molecule
DB02585 4-(Hydroxymethyl)BenzamidineDrugbanksmall molecule
DB03127 BenzamidineDrugbanksmall molecule
DB03129 Diamino-N-[3-(1,3,2-dioxaborolan-2-yloxy)propyl]methaniminiumDrugbanksmall molecule
DB03637 Guanidine-3-propanolDrugbanksmall molecule
DB04109 [4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]BenzamidineDrugbanksmall molecule
DB04369 1,3,2-Dioxaborolan-2-OlDrugbanksmall molecule