Entity Details

Primary name SESN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP58004
EntryNameSESN2_HUMAN
FullNameSestrin-2
TaxID9606
Evidenceevidence at protein level
Length480
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesSESN2

GO terms

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GOName
GO:0001932 regulation of protein phosphorylation
GO:0005092 GDP-dissociation inhibitor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006111 regulation of gluconeogenesis
GO:0006635 fatty acid beta-oxidation
GO:0009749 response to glucose
GO:0016239 positive regulation of macroautophagy
GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
GO:0030308 negative regulation of cell growth
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0031588 nucleotide-activated protein kinase complex
GO:0031932 TORC2 complex
GO:0032042 mitochondrial DNA metabolic process
GO:0032542 sulfiredoxin activity
GO:0032868 response to insulin
GO:0034198 cellular response to amino acid starvation
GO:0034599 cellular response to oxidative stress
GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0042149 cellular response to glucose starvation
GO:0042593 glucose homeostasis
GO:0043491 protein kinase B signaling
GO:0046323 glucose import
GO:0070328 triglyceride homeostasis
GO:0070728 leucine binding
GO:0071230 cellular response to amino acid stimulus
GO:0071233 cellular response to leucine
GO:0072593 reactive oxygen species metabolic process
GO:0098869 cellular oxidant detoxification
GO:1900182 positive regulation of protein localization to nucleus
GO:1901031 regulation of response to reactive oxygen species
GO:1902010 negative regulation of translation in response to endoplasmic reticulum stress
GO:1904262 negative regulation of TORC1 signaling
GO:1904504 positive regulation of lipophagy
GO:1990253 cellular response to leucine starvation
GO:2000479 regulation of cAMP-dependent protein kinase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR006730 SestrinFamilyFamily
IPR029032 AhpD-likeFamilyHomologous superfamily

Diseases

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