Entity Details

Primary name ELF3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78545
EntryNameELF3_HUMAN
FullNameETS-related transcription factor Elf-3
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesELF3

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001824 blastocyst development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006954 inflammatory response
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
GO:0030855 epithelial cell differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060056 mammary gland involution
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000418 Ets domainDomainDomain
IPR003118 Pointed domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR033074 ETS-related transcription factor Elf-3FamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR042693 ETS-related transcription factor Elf-3, pointed domainDomainDomain

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
ELF3_HUMANUB2D1_HUMANIntAct19549727 details
ELF3_HUMANUB2D2_HUMANIntAct19549727 details
ELF3_HUMANKPCI_HUMANIntAct26977885 details
ELF3_HUMANAPBA3_HUMANUniProt26948053 details
ELF3_HUMANNF2L2_HUMANIntAct32911434 details
ELF3_HUMANNFKB1_HUMANBioGRID, HPRD11036073 23687337 details
ELF3_HUMANMED23_HUMANBioGRID, HPRD12242338 12708845 15025473 23464919 details
ELF3_HUMANTBP_HUMANBioGRID10391676 details
ELF3_HUMANTAF9_HUMANBioGRID, HPRD10821850 details
ELF3_HUMANPAK1_HUMANBioGRID17491012 details
ELF3_HUMANMYC_HUMANBioGRID, HPRD1651323 details
ELF3_HUMANXRCC6_HUMANBioGRID15075319 details
ELF3_HUMANXRCC5_HUMANBioGRID15075319 details
ELF3_HUMANANDR_HUMANBioGRID23435425 details
ELF3_HUMANSOX9_HUMANBioGRID27310669 details
ELF3_HUMANEPS15_HUMANHPRD10064583 details
ELF3_HUMANKRT36_HUMANIntAct17353931 details
ELF3_HUMANNLRC3_HUMANIntAct17353931 details
ELF3_HUMANH2B1C_HUMANIntAct17353931 details
ELF3_HUMANEWS_HUMANIntAct17353931 details
ELF3_HUMANPSMD6_HUMANIntAct17353931 details
ELF3_HUMANGARS_HUMANIntAct17353931 details
ELF3_HUMANMOES_HUMANIntAct17353931 details
ELF3_HUMANAKAP9_HUMANIntAct17353931 details
ELF3_HUMANSPG7_HUMANIntAct17353931 details
ELF3_HUMANGLU2B_HUMANIntAct17353931 details
ELF3_HUMANKCTD5_HUMANIntAct17353931 details
ELF3_HUMANNUDC_HUMANIntAct17353931 details
ELF3_HUMANKRT37_HUMANIntAct17353931 details
ELF3_HUMANPA24A_HUMANIntAct17353931 details
ELF3_HUMANKR111_HUMANIntAct17353931 details
ELF3_HUMANFSCN1_HUMANIntAct17353931 details
ELF3_HUMANETFA_HUMANIntAct17353931 details
ELF3_HUMANTF65_HUMANBioGRID, IntAct23687337 25926267 details
ELF3_HUMANFBW1A_HUMANBioGRID17491012 details
ELF3_HUMANEP300_HUMANBioGRID, HPRD15075319 details
ELF3_HUMANRL6_HUMANBioGRID15075319 details
ELF3_HUMANCBR3_HUMANBioGRID15075319 details
ELF3_HUMANG45IP_HUMANBioGRID19801644 details
ELF3_HUMANELF3_HUMANBioGRID17148437 details
ELF3_HUMANEGFR_HUMANHPRD1651322 details
ELF3_HUMANJUN_HUMANHPRD1651323 details
ELF3_HUMANCBP_HUMANHPRD15075319 details