Entity Details

Primary name DEF5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01523
EntryNameDEF5_HUMAN
FullNameDefensin-5
TaxID9606
Evidenceevidence at protein level
Length94
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesDEFA5

GO terms

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GOName
GO:0002227 innate immune response in mucosa
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0030133 transport vesicle
GO:0030496 midbody
GO:0031640 killing of cells of other organism
GO:0034774 secretory granule lumen
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0050832 defense response to fungus
GO:0051673 membrane disruption in other organism
GO:0051873 killing by host of symbiont cells
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0071222 cellular response to lipopolysaccharide
GO:1905710 positive regulation of membrane permeability

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Secreted

Domains

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DomainNameCategoryType
IPR002366 Defensin propeptideDomainDomain
IPR006080 Beta/alpha defensinDomainDomain
IPR006081 Alpha-defensinDomainDomain
IPR016327 Alpha-defensin propeptideFamilyFamily

Diseases

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Interactions

4 interactions