Entity Details

Primary name CD226
Entity type gene
Source Source Link

Details

PrimaryID10666
RefseqGene
SymbolCD226
NameCD226 molecule
Chromosome18
Location18q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCD226_HUMAN

GO terms

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GOName
GO:0002729 positive regulation of natural killer cell cytokine production
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 positive regulation of immunoglobulin mediated immune response
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0008037 cell recognition
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0019901 protein kinase binding
GO:0032729 positive regulation of interferon-gamma production
GO:0033005 positive regulation of mast cell activation
GO:0045121 membrane raft
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050776 regulation of immune response
GO:0050839 cell adhesion molecule binding
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
CD226NECTIN2BioGRID, HPRD, IntAct12913096 15536144 21982860 details
CD226PVRBioGRID, HPRD, IntAct12913096 21982860 details
CD226CD226IntAct25465800 details
CD226TIGITIntAct25465800 details
CD226ITGB2BioGRID, HPRD10591186 details
CD226FYNBioGRID, HPRD10591186 details