Entity Details

Primary name CTSL
Entity type gene
Source Source Link

Details

PrimaryID1514
RefseqGene
SymbolCTSL
Namecathepsin L
Chromosome9
Location9q21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-05-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCATL1_HUMAN

GO terms

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GOName
GO:0001968 fibronectin binding
GO:0002224 toll-like receptor signaling pathway
GO:0002250 adaptive immune response
GO:0004197 cysteine-type endopeptidase activity
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005771 multivesicular body
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006955 immune response
GO:0008234 cysteine-type peptidase activity
GO:0016324 apical plasma membrane
GO:0016540 protein autoprocessing
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0019065 receptor-mediated endocytosis of virus by host cell
GO:0019882 antigen processing and presentation
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617 extracellular matrix disassembly
GO:0030574 collagen catabolic process
GO:0031638 zymogen activation
GO:0034230 enkephalin processing
GO:0036021 endolysosome lumen
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0042393 histone binding
GO:0042583 chromaffin granule
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043373 CD4-positive, alpha-beta T cell lineage commitment
GO:0043394 proteoglycan binding
GO:0045616 regulation of keratinocyte differentiation
GO:0046718 viral entry into host cell
GO:0048002 antigen processing and presentation of peptide antigen
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0060309 elastin catabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0071682 endocytic vesicle lumen
GO:0071888 macrophage apoptotic process
GO:0097067 cellular response to thyroid hormone stimulus
GO:0097655 serpin family protein binding

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
CTSLGEMBioGRID, IntAct18624398 details
CTSLRELBBioGRID, IntAct21988832 details
CTSLBTN3A3BioGRID, IntAct21988832 details
CTSLPPP1CCBioGRID, IntAct21382349 details
CTSLCRELD2MINT21900206 details
CTSLEEDBioGRID, MINT21900206 details
CTSLSGTABioGRID, IntAct25416956 details
CTSLCSTABioGRID, HPRD12921779 9585570 details
CTSLRXRABioGRID, HPRD9837884 9918848 details
CTSLSERPINB3BioGRID, HPRD12949073 9548757 details
CTSLBAG6BioGRID21900206 details
CTSLMCPH1BioGRID29150431 details
CTSLCST7BioGRID, HPRD, IntAct28514442 9632704 9733783 details
CTSLH3C14BioGRID21326229 details
CTSLSLPIHPRD11435427 details
CTSLCTSLHPRD9585570 details
CTSLCUX1HPRD15099520 details
CTSLCOL18A1HPRD10716919 details
CTSLIGFBP3HPRD11801256 details
CTSLCXCL8HPRD12818188 details
CTSLCD7HPRD8666891 details
CTSLTGHPRD1939080 details
CTSLPLAUHPRD1551416 details
CTSLKNG1HPRD11517935 details
CTSLCSTBHPRD11514663 details
CTSLCTSCHPRD11327826 details
CTSLCST3HPRD10428479 details
CTSLSERPINB13HPRD12504904 12809493 details
CTSLARSAHPRD11777924 details
CTSLCD74HPRD10022822 details
CTSLGCGHPRD7340337 details
CTSLAPOA1BioGRID, IntAct15174051 details
CTSLALBBioGRID, IntAct15174051 details
CTSLTFIntAct15174051 details
CTSLCST1BioGRID, IntAct28514442 details
CTSLCTSKBioGRID, IntAct28514442 details
CTSLCTSVBioGRID, IntAct26186194 28514442 details
CTSLCCDC88ABioGRID, IntAct26186194 28514442 details
CTSLCLTCL1BioGRID, IntAct26186194 28514442 details
CTSLCTSHBioGRID, IntAct26186194 28514442 details
CTSLPGDBioGRID26344197 details
CTSLMOV10BioGRID22658674 details
CTSLNXF1BioGRID22658674 details
CTSLTNIP2BioGRID27609421 details
CTSLDDX58BioGRID32513696 details