Entity Details

Primary name GAS6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14393
EntryNameGAS6_HUMAN
FullNameGrowth arrest-specific protein 6
TaxID9606
Evidenceevidence at protein level
Length678
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesGAS6

GO terms

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GOName
GO:0001764 neuron migration
GO:0001786 phosphatidylserine binding
GO:0001934 positive regulation of protein phosphorylation
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0002576 platelet degranulation
GO:0003104 positive regulation of glomerular filtration
GO:0005102 signaling receptor binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0006468 protein phosphorylation
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006909 phagocytosis
GO:0007165 signal transduction
GO:0007167 enzyme linked receptor protein signaling pathway
GO:0007596 blood coagulation
GO:0009267 cellular response to starvation
GO:0010628 positive regulation of gene expression
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0018105 peptidyl-serine phosphorylation
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0019079 viral genome replication
GO:0030296 protein tyrosine kinase activator activity
GO:0030674 protein-macromolecule adaptor activity
GO:0030971 receptor tyrosine kinase binding
GO:0031093 platelet alpha granule lumen
GO:0031100 animal organ regeneration
GO:0031589 cell-substrate adhesion
GO:0032008 positive regulation of TOR signaling
GO:0032148 activation of protein kinase B activity
GO:0032689 negative regulation of interferon-gamma production
GO:0032692 negative regulation of interleukin-1 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032825 positive regulation of natural killer cell differentiation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035457 cellular response to interferon-alpha
GO:0035690 cellular response to drug
GO:0035754 B cell chemotaxis
GO:0040008 regulation of growth
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277 apoptotic cell clearance
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043491 protein kinase B signaling
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045860 positive regulation of protein kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046718 viral entry into host cell
GO:0046813 receptor-mediated virion attachment to host cell
GO:0046827 positive regulation of protein export from nucleus
GO:0048018 receptor ligand activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0050766 positive regulation of phagocytosis
GO:0050900 leukocyte migration
GO:0051897 positive regulation of protein kinase B signaling
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:0070062 extracellular exosome
GO:0070168 negative regulation of biomineral tissue development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070588 calcium ion transmembrane transport
GO:0071307 cellular response to vitamin K
GO:0071333 cellular response to glucose stimulus
GO:0071363 cellular response to growth factor stimulus
GO:0072659 protein localization to plasma membrane
GO:0085029 extracellular matrix assembly
GO:0097028 dendritic cell differentiation
GO:0097241 hematopoietic stem cell migration to bone marrow
GO:1900142 negative regulation of oligodendrocyte apoptotic process
GO:2000270 negative regulation of fibroblast apoptotic process
GO:2000352 negative regulation of endothelial cell apoptotic process
GO:2000510 positive regulation of dendritic cell chemotaxis
GO:2000533 negative regulation of renal albumin absorption
GO:2000669 negative regulation of dendritic cell apoptotic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domainDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001791 Laminin G domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013032 EGF-like, conserved siteSiteConserved site
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR017857 Coagulation factor-like, Gla domain superfamilyFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR026823 Complement Clr-like EGF domainDomainDomain
IPR035972 Gamma-carboxyglutamic acid-rich (GLA) domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions