Entity Details

Primary name MTF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14872
EntryNameMTF1_HUMAN
FullNameMetal regulatory transcription factor 1
TaxID9606
Evidenceevidence at protein level
Length753
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesMTF1

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006979 response to oxidative stress
GO:0007417 central nervous system development
GO:0010038 response to metal ion
GO:0035035 histone acetyltransferase binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046686 response to cadmium ion
GO:0046872 metal ion binding
GO:0071294 cellular response to zinc ion
GO:1990079 cartilage homeostasis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR029796 Metal regulatory transcription factor 1FamilyFamily
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule
DB12965 SilverDrugbanksmall molecule

Interactions

5 interactions