Entity Details

Primary name HERP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15011
EntryNameHERP1_HUMAN
FullNameHomocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
TaxID9606
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesHERPUD1

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006986 response to unfolded protein
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0031396 regulation of protein ubiquitination
GO:0032469 endoplasmic reticulum calcium ion homeostasis
GO:0034976 response to endoplasmic reticulum stress
GO:0036499 PERK-mediated unfolded protein response
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044322 endoplasmic reticulum quality control compartment
GO:0044325 transmembrane transporter binding
GO:0045047 protein targeting to ER
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:1990037 Lewy body core
GO:1990756 ubiquitin ligase-substrate adaptor activity
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR039751 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 /2FamilyFamily

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
HERP1_HUMANLFA3_HUMANBioGRID, HPRD, IntAct16169070 details
HERP1_HUMANRFA2_HUMANBioGRID, HPRD, IntAct16169070 details
HERP1_HUMANSTAR9_HUMANBioGRID, HPRD, IntAct16169070 details
HERP1_HUMANIMPA2_HUMANHPRD, IntAct16169070 details
HERP1_HUMANEWS_HUMANBioGRID, HPRD, IntAct16189514 details
HERP1_HUMANUBP7_HUMANBioGRID, HPRD, IntAct16713569 details
HERP1_HUMANTOLIP_HUMANBioGRID, IntAct20936779 details
HERP1_HUMANGDIR1_HUMANBioGRID, MINT21900206 details
HERP1_HUMANXRCC6_HUMANBioGRID, MINT21900206 details
HERP1_HUMANAMFR_HUMANBioGRID, DIP17310145 19223579 21636303 21965653 24366945 24496447 25409783 26424800 details
HERP1_HUMANC5AR2_HUMANBioGRID, MINT28298427 details
HERP1_HUMANCCR2_HUMANBioGRID, MINT28298427 details
HERP1_HUMANPAR2_HUMANBioGRID, MINT28298427 details
HERP1_HUMANACM2_HUMANBioGRID, MINT28298427 details
HERP1_HUMANSYVN1_HUMANBioGRID, UniProt16289116 21149444 23867461 26424800 26471130 28827405 31056421 32614325 32738194 details
HERP1_HUMANTERA_HUMANBioGRID16289116 details
HERP1_HUMANA4_HUMANBioGRID21832049 details
HERP1_HUMANSH3R1_HUMANBioGRID17420289 details
HERP1_HUMANUBXN6_HUMANUniProt18656546 details
HERP1_HUMANPSN1_HUMANBioGRID, HPRD11799129 14550564 details
HERP1_HUMANUBQL1_HUMANBioGRID18307982 details
HERP1_HUMANUBQL2_HUMANBioGRID, HPRD18307982 30442662 details
HERP1_HUMANUBQL4_HUMANBioGRID18307982 details
HERP1_HUMANDERL1_HUMANBioGRID16289116 details
HERP1_HUMANSELS_HUMANBioGRID16289116 details
HERP1_HUMANSYUA_HUMANBioGRID20604806 details
HERP1_HUMANSNCAP_HUMANBioGRID20604806 details
HERP1_HUMANSIAH1_HUMANBioGRID20604806 details
HERP1_HUMANPSMD2_HUMANBioGRID21149444 details
HERP1_HUMANUBC_HUMANBioGRID14550564 details
HERP1_HUMANIL1R1_HUMANBioGRID20054003 details
HERP1_HUMANIL23A_HUMANBioGRID20054003 details
HERP1_HUMANDERL2_HUMANBioGRID23867461 details
HERP1_HUMANTBK1_HUMANBioGRID28954889 details
HERP1_HUMANHD_HUMANBioGRID29430620 details
HERP1_HUMANCD3D_HUMANHPRD18307982 details