Entity Details

Primary name HMOX1
Entity type gene
Source Source Link

Details

PrimaryID3162
RefseqGeneNG_023030
SymbolHMOX1
Nameheme oxygenase 1
Chromosome22
Location22q12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-05-17
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsHMOX1_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001935 endothelial cell proliferation
GO:0002246 wound healing involved in inflammatory response
GO:0002686 negative regulation of leukocyte migration
GO:0004392 heme oxygenase (decyclizing) activity
GO:0004630 phospholipase D activity
GO:0005198 structural molecule activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005901 caveola
GO:0006788 heme oxidation
GO:0006879 cellular iron ion homeostasis
GO:0006979 response to oxidative stress
GO:0007264 small GTPase mediated signal transduction
GO:0007588 excretion
GO:0008217 regulation of blood pressure
GO:0008219 cell death
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010656 negative regulation of muscle cell apoptotic process
GO:0014806 smooth muscle hyperplasia
GO:0016020 membrane
GO:0016239 positive regulation of macroautophagy
GO:0016242 negative regulation of macroautophagy
GO:0019221 cytokine-mediated signaling pathway
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0031670 cellular response to nutrient
GO:0032722 positive regulation of chemokine production
GO:0032764 negative regulation of mast cell cytokine production
GO:0034101 erythrocyte homeostasis
GO:0034383 low-density lipoprotein particle clearance
GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034605 cellular response to heat
GO:0035094 response to nicotine
GO:0035556 intracellular signal transduction
GO:0042167 heme catabolic process
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043305 negative regulation of mast cell degranulation
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627 response to estrogen
GO:0045048 protein insertion into ER membrane
GO:0045765 regulation of angiogenesis
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0055072 iron ion homeostasis
GO:0071243 cellular response to arsenic-containing substance
GO:0071276 cellular response to cadmium ion
GO:0071456 cellular response to hypoxia
GO:0072719 cellular response to cisplatin
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0097421 liver regeneration
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:1904036 negative regulation of epithelial cell apoptotic process
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation

Diseases

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Interactions

70 interactions

InteractorPartnerSourcesPublicationsLink
HMOX1CREB3BioGRID, IntAct, MINT21516116 31515488 details
HMOX1ASLBioGRID, IntAct21988832 details
HMOX1TERF1bhf-ucl, BioGRID21044950 details
HMOX1POT1bhf-ucl, BioGRID21044950 details
HMOX1STX1ABioGRID, IntAct32296183 details
HMOX1MSMO1BioGRID, IntAct32296183 details
HMOX1CYB561BioGRID, IntAct32296183 details
HMOX1ELOVL6BioGRID, IntAct32296183 details
HMOX1TMEM14BBioGRID, IntAct32296183 details
HMOX1TM4SF19BioGRID, IntAct32296183 details
HMOX1ERGIC3BioGRID, IntAct32296183 details
HMOX1ELOVL4BioGRID, IntAct32296183 details
HMOX1FAM174ABioGRID, IntAct32296183 details
HMOX1PDZK1IP1BioGRID, IntAct32296183 details
HMOX1JAGN1BioGRID, IntAct32296183 details
HMOX1AQP6BioGRID, IntAct32296183 details
HMOX1SEC11CBioGRID, IntAct32296183 details
HMOX1TLCD4BioGRID, IntAct32296183 details
HMOX1GPR152BioGRID, IntAct32296183 details
HMOX1COQ9BioGRID, IntAct32296183 details
HMOX1ARL13BBioGRID, IntAct32296183 details
HMOX1FAM210BBioGRID, IntAct32296183 details
HMOX1FAM209ABioGRID, IntAct32296183 details
HMOX1CPLX4BioGRID, IntAct32296183 details
HMOX1SLC16A7BioGRID, IntAct32296183 details
HMOX1CD79ABioGRID, IntAct32296183 details
HMOX1CYBRD1BioGRID, IntAct32296183 details
HMOX1CRB3BioGRID, IntAct32296183 details
HMOX1ELOVL5BioGRID, IntAct32296183 details
HMOX1PTGER4BioGRID, MINT28298427 details
HMOX1SMOBioGRID, MINT28298427 details
HMOX1KASH5BioGRID25416956 details
HMOX1LMNABioGRID24623722 details
HMOX1TMIEBioGRID32296183 details
HMOX1HMOX1BioGRID, HPRD12500973 details
HMOX1UFD1BioGRID18544348 details
HMOX1PSMD2BioGRID18544348 details
HMOX1SQSTM1BioGRID31521246 details
HMOX1SIAH2BioGRID32042051 details
HMOX1AKT1HPRD15581622 details
HMOX1PORHPRD12626517 details
HMOX1BLVRBHPRD12626517 details
HMOX1NOS1HPRD11849436 details
HMOX1ADGRE5BioGRID, IntAct28514442 details
HMOX1PCDHAC2BioGRID, IntAct28514442 details
HMOX1C5AR2BioGRID, IntAct28514442 details
HMOX1CDK15BioGRID, IntAct28514442 details
HMOX1TBC1D22BBioGRID, IntAct28514442 details
HMOX1DDX19BBioGRID, IntAct26186194 28514442 details
HMOX1SRPRBBioGRID, IntAct26186194 28514442 details
HMOX1STIM2BioGRID, IntAct28514442 details
HMOX1ADAM33BioGRID, IntAct28514442 details
HMOX1SLC39A8BioGRID, IntAct28514442 details
HMOX1CDC20BBioGRID, IntAct26186194 28514442 details
HMOX1LRRC27BioGRID, IntAct28514442 details
HMOX1TEX264BioGRID, IntAct26186194 28514442 details
HMOX1UGT8BioGRID, IntAct26186194 28514442 details
HMOX1HLA-CBioGRID, IntAct26186194 28514442 details
HMOX1SYVN1BioGRID, IntAct22119785 details
HMOX1DERL1BioGRID, IntAct22119785 details
HMOX1NRG1BioGRID26186194 details
HMOX1ZSCAN20BioGRID26186194 details
HMOX1CHRNA9BioGRID26186194 details
HMOX1RNF4BioGRID29180619 details
HMOX1NRASBioGRID30194290 details
HMOX1KRASBioGRID30194290 details
HMOX1NPC1BioGRID33144569 details
HMOX1ELAVL1BioGRID19322201 details
HMOX1TUT1BioGRID21102410 details
HMOX1CPSF1BioGRID21102410 details