Entity Details

Primary name OASL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15646
EntryNameOASL_HUMAN
FullName2'-5'-oligoadenylate synthase-like protein
TaxID9606
Evidenceevidence at protein level
Length514
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesOASL

GO terms

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GOName
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009615 response to virus
GO:0016020 membrane
GO:0016779 nucleotidyltransferase activity
GO:0045071 negative regulation of viral genome replication
GO:0046966 thyroid hormone receptor binding
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060700 regulation of ribonuclease activity
GO:0070106 interleukin-27-mediated signaling pathway
GO:1900246 positive regulation of RIG-I signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR006116 2-5OAS/ClassI-CCAase, nucleotidyltransferase domainDomainDomain
IPR006117 2-5-oligoadenylate synthetase, C-terminal conserved siteSiteConserved site
IPR018952 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminalDomainDomain
IPR026774 2'-5'-oligoadenylate synthaseFamilyFamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR043518 2-5-oligoadenylate synthetase, N-terminal conserved siteSiteConserved site
IPR043519 Nucleotidyltransferase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions