Entity Details

Primary name TBX3
Entity type gene
Source Source Link

Details

PrimaryID6926
RefseqGeneNG_008315
SymbolTBX3
NameT-box transcription factor 3
Chromosome12
Location12q24.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-12-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTBX3_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 DNA-binding transcription activator activity
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001708 cell fate specification
GO:0001947 heart looping
GO:0003151 outflow tract morphogenesis
GO:0003167 atrioventricular bundle cell differentiation
GO:0003205 cardiac chamber development
GO:0003272 endocardial cushion formation
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007417 central nervous system development
GO:0007569 cell aging
GO:0008284 positive regulation of cell population proliferation
GO:0008595 anterior/posterior axis specification, embryo
GO:0009887 animal organ morphogenesis
GO:0010159 specification of animal organ position
GO:0019827 stem cell population maintenance
GO:0021761 limbic system development
GO:0030539 male genitalia development
GO:0030540 female genitalia development
GO:0030857 negative regulation of epithelial cell differentiation
GO:0030879 mammary gland development
GO:0032275 luteinizing hormone secretion
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035136 forelimb morphogenesis
GO:0036302 atrioventricular canal development
GO:0042733 embryonic digit morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045662 negative regulation of myoblast differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046884 follicle-stimulating hormone secretion
GO:0048332 mesoderm morphogenesis
GO:0051145 smooth muscle cell differentiation
GO:0060021 roof of mouth development
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0060412 ventricular septum morphogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060596 mammary placode formation
GO:0060923 cardiac muscle cell fate commitment
GO:0060931 sinoatrial node cell development
GO:0072105 ureteric peristalsis
GO:0090398 cellular senescence
GO:1905072 cardiac jelly development
GO:1905222 atrioventricular canal morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis
GO:2000648 positive regulation of stem cell proliferation

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
TBX3TOLLIPBioGRID, IntAct20936779 details
TBX3TLE5BioGRID, IntAct25416956 details
TBX3CA8BioGRID, IntAct25416956 details
TBX3PRR20ABioGRID, IntAct32296183 details
TBX3PRR20BBioGRID, IntAct32296183 details
TBX3PRR20CBioGRID, IntAct32296183 details
TBX3PRR20DBioGRID, IntAct32296183 details
TBX3PRR20EBioGRID, IntAct32296183 details
TBX3UFSP1BioGRID, IntAct32296183 details
TBX3PFDN5BioGRID, IntAct32296183 details
TBX3PLEKHF2BioGRID21516116 details
TBX3SIRPABioGRID19299420 details
TBX3CSF3BioGRID32296183 details
TBX3ZNF34BioGRID32296183 details
TBX3TBX3BioGRID, HPRD12005433 details
TBX3HDAC1BioGRID18245468 details
TBX3HDAC2BioGRID18245468 details
TBX3HDAC3BioGRID18245468 details
TBX3HDAC5BioGRID18245468 details
TBX3PMLBioGRID22002537 details
TBX3CDCA5BioGRID, IntAct26496610 details
TBX3DCP1ABioGRID, IntAct26496610 details
TBX3MAPK3BioGRID, IntAct26496610 details
TBX3KIF21BBioGRID, IntAct26496610 details
TBX3DNAJC11BioGRID, IntAct26496610 details
TBX3CDK8BioGRID, IntAct26496610 details
TBX3KIF21ABioGRID, IntAct26496610 details
TBX3HNRNPLLBioGRID, IntAct28514442 details
TBX3SOX2BioGRID, MINT23667531 details
TBX3CTNNB1BioGRID27684187 details
TBX3LMNABioGRID27684187 details
TBX3CALM1BioGRID27684187 details
TBX3EIF4A3BioGRID27684187 details
TBX3XRCC5BioGRID27684187 details
TBX3SLC25A3BioGRID27684187 details
TBX3EWSR1BioGRID27684187 details
TBX3TMPOBioGRID27684187 details
TBX3HDAC4BioGRID27684187 details
TBX3DHX9BioGRID27684187 details
TBX3HNRNPKBioGRID27684187 details
TBX3SVILBioGRID27684187 details
TBX3EMDBioGRID27684187 details
TBX3MYL6BioGRID27684187 details
TBX3USP10BioGRID27684187 details
TBX3NUFIP2BioGRID27684187 details
TBX3HSPA8BioGRID27684187 details
TBX3ATP5F1BBioGRID27684187 details
TBX3PABPC4BioGRID27684187 details
TBX3PDIA3BioGRID27684187 details
TBX3RPS27ABioGRID27684187 details
TBX3XRCC6BioGRID27684187 details
TBX3HSPA1ABioGRID27684187 details
TBX3RBMXBioGRID27684187 details
TBX3H4C1BioGRID30804502 details
TBX3SP100BioGRID31753913 details
TBX3ELAVL1BioGRID19322201 details
TBX3NONOBioGRID31815296 details
TBX3MKRN2BioGRID32460013 details