Entity Details

Primary name LAPTM5
Entity type gene
Source Source Link

Details

PrimaryID7805
RefseqGene
SymbolLAPTM5
Namelysosomal protein transmembrane 5
Chromosome1
Location1p35.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLAPM5_HUMAN

GO terms

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GOName
GO:0002357 defense response to tumor cell
GO:0002720 positive regulation of cytokine production involved in immune response
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005887 integral component of plasma membrane
GO:0006622 protein targeting to lysosome
GO:0006886 intracellular protein transport
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0012502 induction of programmed cell death
GO:0030133 transport vesicle
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031625 ubiquitin protein ligase binding
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032991 protein-containing complex
GO:0043410 positive regulation of MAPK cascade
GO:0048471 perinuclear region of cytoplasm
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050868 negative regulation of T cell activation
GO:0050869 negative regulation of B cell activation
GO:0060907 positive regulation of macrophage cytokine production
GO:0090160 Golgi to lysosome transport
GO:0097214 positive regulation of lysosomal membrane permeability
GO:0140036 ubiquitin-dependent protein binding
GO:0140311 protein sequestering activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
GO:1904093 negative regulation of autophagic cell death
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
GO:2000646 positive regulation of receptor catabolic process

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
LAPTM5SMURF2BioGRID, HPRD, MINT15231748 details
LAPTM5HEYLBioGRID, HPRD, MINT15231748 details
LAPTM5DCUN1D1BioGRID, HPRD, MINT15231748 details
LAPTM5HEY1BioGRID, HPRD, MINT15231748 details
LAPTM5ANKRD13ABioGRID, HPRD, MINT15231748 details
LAPTM5EPN3BioGRID, HPRD, MINT15231748 details
LAPTM5UBA52BioGRID, HPRD, MINT15231748 details
LAPTM5USP13BioGRID, HPRD, MINT15231748 details
LAPTM5TNFAIP3BioGRID, HPRD, MINT15231748 22733818 details
LAPTM5WWP1BioGRID, HPRD, MINT15231748 details
LAPTM5RNF168BioGRID, HPRD, MINT15231748 details
LAPTM5NEDD4BioGRID, MINT15231748 17116753 19953087 details
LAPTM5EPS15BioGRID, HPRD, MINT15231748 details
LAPTM5EPN1BioGRID, HPRD, MINT15231748 details
LAPTM5NEDD4LBioGRID, HPRD, MINT15231748 details
LAPTM5TOM1L2BioGRID, HPRD, MINT15231748 details
LAPTM5LDLRAD1BioGRID, IntAct25416956 details
LAPTM5DISP1BioGRID, IntAct25416956 details
LAPTM5AIG1BioGRID, IntAct32296183 details
LAPTM5CYB5R3BioGRID, IntAct32296183 details
LAPTM5UBE2J1BioGRID, IntAct32296183 details
LAPTM5MRPL18BioGRID, IntAct32296183 details
LAPTM5HMOX2BioGRID, IntAct32296183 details
LAPTM5RPRMBioGRID, IntAct32296183 details
LAPTM5C4orf3BioGRID, IntAct32296183 details
LAPTM5VAMP1BioGRID, IntAct32296183 details
LAPTM5CLDN19BioGRID, IntAct32296183 details
LAPTM5GYPABioGRID, IntAct32296183 details
LAPTM5RTP2BioGRID, IntAct32296183 details
LAPTM5INSIG2BioGRID, IntAct32296183 details
LAPTM5UBCBioGRID17116753 details
LAPTM5ITCHBioGRID22009753 details
LAPTM5SLC22A2BioGRID31318583 details
LAPTM5HERC1HPRD15231748 details
LAPTM5UBAC1HPRD15231748 details
LAPTM5KRT7HPRD15231748 details
LAPTM5HUWE1HPRD15231748 details
LAPTM5EPN2HPRD15231748 details
LAPTM5GGA3BioGRID17116753 details
LAPTM5LAMP1BioGRID22733818 details
LAPTM5HNRNPCBioGRID, IntAct30021884 details
LAPTM5BAG3BioGRID23824909 details