Entity Details

Primary name MMP20
Entity type gene
Source Source Link

Details

PrimaryID9313
RefseqGeneNG_012151
SymbolMMP20
Namematrix metallopeptidase 20
Chromosome11
Location11q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMMP20_HUMAN

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0008270 zinc ion binding
GO:0022617 extracellular matrix disassembly
GO:0030163 protein catabolic process
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0070173 regulation of enamel mineralization
GO:0097186 amelogenesis

Diseases

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Disease IDSourceNameDescription
612529 OMIMAmelogenesis imperfecta, hypomaturation type, 2A2 (AI2A2)A defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
MMP20ACANHPRD10922468 details
MMP20DIABLOBioGRID31536960 details
MMP20FHBioGRID31536960 details
MMP20YWHAEBioGRID31536960 details