Entity Details

Primary name ARHGG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5VV41
EntryNameARHGG_HUMAN
FullNameRho guanine nucleotide exchange factor 16
TaxID9606
Evidenceevidence at protein level
Length709
SequenceStatuscomplete
DateCreated2006-05-02
DateModified2021-06-02

Ontological Relatives

GenesARHGEF16

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0007186 G protein-coupled receptor signaling pathway
GO:0030165 PDZ domain binding
GO:0030971 receptor tyrosine kinase binding
GO:0031267 small GTPase binding
GO:0043065 positive regulation of apoptotic process
GO:0045296 cadherin binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0060326 cell chemotaxis
GO:0090630 activation of GTPase activity
GO:1903078 positive regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035797 ARHGEF16/ARHGEF26, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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