Entity Details

Primary name TTBK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6IQ55
EntryNameTTBK2_HUMAN
FullNameTau-tubulin kinase 2
TaxID9606
Evidenceevidence at protein level
Length1244
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesTTBK2

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0007026 negative regulation of microtubule depolymerization
GO:0007224 smoothened signaling pathway
GO:0018105 peptidyl-serine phosphorylation
GO:0019894 kinesin binding
GO:0021549 cerebellum development
GO:0021681 cerebellar granular layer development
GO:0021935 cerebellar granule cell precursor tangential migration
GO:0030334 regulation of cell migration
GO:0035869 ciliary transition zone
GO:0036064 ciliary basal body
GO:0048156 tau protein binding
GO:0050321 tau-protein kinase activity
GO:0051010 microtubule plus-end binding
GO:0060271 cilium assembly
GO:0097711 ciliary basal body-plasma membrane docking
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902817 negative regulation of protein localization to microtubule
GO:1904527 negative regulation of microtubule binding

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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