Entity Details

Primary name S27A4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6P1M0
EntryNameS27A4_HUMAN
FullNameLong-chain fatty acid transport protein 4
TaxID9606
Evidenceevidence at protein level
Length643
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesSLC27A4

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0001579 medium-chain fatty acid transport
GO:0001676 long-chain fatty acid metabolic process
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0005324 long-chain fatty acid transporter activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0006631 fatty acid metabolic process
GO:0007584 response to nutrient
GO:0015908 fatty acid transport
GO:0015909 long-chain fatty acid transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
GO:0031957 very long-chain fatty acid-CoA ligase activity
GO:0042760 very long-chain fatty acid catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0043588 skin development
GO:0044381 glucose import in response to insulin stimulus
GO:0044539 long-chain fatty acid import into cell
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0047676 arachidonate-CoA ligase activity
GO:0062003 negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
GO:0090433 palmitoyl-CoA ligase activity
GO:0090434 oleoyl-CoA ligase activity
GO:0090630 activation of GTPase activity
GO:0150104 transport across blood-brain barrier
GO:1901480 oleate transmembrane transporter activity
GO:1990379 lipid transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000873 AMP-dependent synthetase/ligaseDomainDomain
IPR020845 AMP-binding, conserved siteSiteConserved site
IPR022272 Lipocalin family conserved siteSiteConserved site
IPR025110 AMP-binding enzyme, C-terminal domainDomainDomain
IPR030304 Fatty acid transport protein 4FamilyFamily
IPR042099 ANL, N-terminal domainFamilyHomologous superfamily

Diseases

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