Entity Details

Primary name EFL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z2Z2
EntryNameEFL1_HUMAN
FullNameElongation factor-like GTPase 1
TaxID9606
Evidenceevidence at protein level
Length1120
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesEFL1

GO terms

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GOName
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0042256 mature ribosome assembly
GO:0043022 ribosome binding
GO:0046039 GTP metabolic process
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000640 Elongation factor EFG, domain V-likeDomainDomain
IPR000795 Translational (tr)-type GTP-binding domainDomainDomain
IPR005225 Small GTP-binding protein domainDomainDomain
IPR009000 Translation protein, beta-barrel domain superfamilyFamilyHomologous superfamily
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035647 EF-G domain III/V-likeFamilyHomologous superfamily
IPR041095 Elongation Factor G, domain IIDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02750 S-(Methylmercury)-L-CysteineDrugbanksmall molecule
DB03619 Deoxycholic acidDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
EFL1_HUMANSBDS_HUMANBioGRID, IntAct26344197 30545121 details