Entity Details

Primary name APLF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IW19
EntryNameAPLF_HUMAN
FullNameAprataxin and PNK-like factor
TaxID9606
Evidenceevidence at protein level
Length511
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesAPLF

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000166 nucleotide binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004520 endodeoxyribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006302 double-strand break repair
GO:0006974 cellular response to DNA damage stimulus
GO:0008408 3'-5' exonuclease activity
GO:0035861 site of double-strand break
GO:0046872 metal ion binding
GO:0051106 positive regulation of DNA ligation

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000253 Forkhead-associated (FHA) domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR019406 Aprataxin and PNK-like factor, PBZ domainDomainDomain
IPR039253 Aprataxin and PNK-like factorFamilyFamily
IPR041388 PNK, FHA domainDomainDomain

Diseases

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