Entity Details

Primary name SP8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IXZ3
EntryNameSP8_HUMAN
FullNameTranscription factor Sp8
TaxID9606
Evidenceevidence at protein level
Length490
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesSP8

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009953 dorsal/ventral pattern formation
GO:0009954 proximal/distal pattern formation
GO:0030326 embryonic limb morphogenesis
GO:0046872 metal ion binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SP8_HUMANSDCB1_HUMANMINT26787460 details
SP8_HUMANHEYL_HUMANBioGRID, IntAct20211142 details
SP8_HUMANZN519_HUMANBioGRID, IntAct20211142 details
SP8_HUMANZN273_HUMANBioGRID, IntAct20211142 details