Entity Details

Primary name PALS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N3R9
EntryNamePALS1_HUMAN
FullNameProtein PALS1
TaxID9606
Evidenceevidence at protein level
Length675
SequenceStatuscomplete
DateCreated2003-01-10
DateModified2021-06-02

Ontological Relatives

GenesPALS1

GO terms

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GOName
GO:0002011 morphogenesis of an epithelial sheet
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0010467 gene expression
GO:0016324 apical plasma membrane
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0019904 protein domain specific binding
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0030424 axon
GO:0032287 peripheral nervous system myelin maintenance
GO:0032288 myelin assembly
GO:0032991 protein-containing complex
GO:0035749 myelin sheath adaxonal region
GO:0035750 protein localization to myelin sheath abaxonal region
GO:0043204 perikaryon
GO:0043219 lateral loop
GO:0043220 Schmidt-Lanterman incisure
GO:0070062 extracellular exosome
GO:0070830 bicellular tight junction assembly
GO:0072659 protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell junction
Cell membrane
Cell projection
Endomembrane system
Endoplasmic reticulum-Golgi intermediate compartment
Golgi apparatus
Perikaryon

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR004172 L27 domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR014775 L27 domain, C-terminalDomainDomain
IPR015145 L27-NDomainDomain
IPR020590 Guanylate kinase, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035601 MPP5, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036892 L27 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

30 interactions

InteractorPartnerSourcesPublicationsLink
PALS1_HUMANCRUM1_HUMANIntAct, MINT, UniProt11927608 17920587 33758649 details
PALS1_HUMANLIN7A_HUMANBioGRID, HPRD, IntAct10753959 23718855 24366813 25416956 28514442 31515488 32296183 details
PALS1_HUMANLIN7C_HUMANBioGRID, IntAct24366813 26186194 28514442 32296183 details
PALS1_HUMANSOCS4_HUMANBioGRID, IntAct25814554 details
PALS1_HUMANFTCD_HUMANBioGRID, IntAct32296183 details
PALS1_HUMANSNTG2_HUMANBioGRID, IntAct32296183 details
PALS1_HUMANDLGP4_HUMANBioGRID, IntAct32296183 details
PALS1_HUMANTRAF2_HUMANBioGRID, IntAct32296183 details
PALS1_HUMANLIN7B_HUMANBioGRID, IntAct28514442 32296183 details
PALS1_HUMANBHLH9_HUMANBioGRID, IntAct32296183 details
PALS1_HUMANCDC42_HUMANIntAct21311754 details
PALS1_HUMANCRUM3_HUMANBioGRID, HPRD, IntAct12527193 12771187 20861307 details
PALS1_HUMANFGFR3_HUMANIntAct32814053 details
PALS1_HUMANGELS_HUMANIntAct32814053 details
PALS1_HUMANTTHY_HUMANIntAct32814053 details
PALS1_HUMANWFS1_HUMANIntAct32814053 details
PALS1_HUMANUBQL1_HUMANIntAct32814053 details
PALS1_HUMANHD_HUMANIntAct32814053 details
PALS1_HUMANATX3_HUMANIntAct32814053 details
PALS1_HUMANE41L5_HUMANUniProt17920587 details
PALS1_HUMANNUMB_HUMANBioGRID32296183 details
PALS1_HUMANMPP4_HUMANHPRD15914641 details
PALS1_HUMANINADL_HUMANIntAct, MINT11927608 21481793 24366813 28514442 details
PALS1_HUMANAMOT_HUMANBioGRID, IntAct16678097 19615732 21481793 24255178 24366813 28514442 34079125 details
PALS1_HUMANAMOL2_HUMANBioGRID, IntAct24255178 27521426 28514442 details
PALS1_HUMANPAR6A_HUMANBioGRID12545177 details
PALS1_HUMANRHG17_HUMANBioGRID16678097 details
PALS1_HUMANZN451_HUMANBioGRID23718855 details
PALS1_HUMANPAR6B_HUMANHPRD12545177 details
PALS1_HUMANARF6_HUMANHPRD16737952 details