Entity Details

Primary name PAR3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00254
EntryNamePAR3_HUMAN
FullNameProteinase-activated receptor 3
TaxID9606
Evidenceevidence at protein level
Length374
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-04-07

Ontological Relatives

GenesF2RL2

GO terms

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GOName
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004930 G protein-coupled receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007596 blood coagulation
GO:0009611 response to wounding
GO:0015057 thrombin-activated receptor activity
GO:0016324 apical plasma membrane
GO:0030168 platelet activation
GO:0032991 protein-containing complex
GO:0035025 positive regulation of Rho protein signal transduction
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR003912 Protease-activated receptorFamilyFamily
IPR003943 Protease-activated receptor 3FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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