Entity Details

Primary name P66B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WXI9
EntryNameP66B_HUMAN
FullNameTranscriptional repressor p66-beta
TaxID9606
Evidenceevidence at protein level
Length593
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesGATAD2B

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0005654 nucleoplasm
GO:0008270 zinc ion binding
GO:0016581 NuRD complex
GO:0016607 nuclear speck
GO:0032991 protein-containing complex
GO:0043044 ATP-dependent chromatin remodeling
GO:0043565 sequence-specific DNA binding

Subcellular Location

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Subcellular Location
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000679 Zinc finger, GATA-typeDomainDomain
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR032346 Transcriptional repressor p66, coiled-coil MBD2-interaction domainDomainDomain
IPR040386 Transcriptional repressor p66FamilyFamily

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
P66B_HUMANSMAD2_HUMANBioGRID, HPRD, MINT15231748 details
P66B_HUMANHDAC1_HUMANBioGRID, IntAct, MINT11756549 16738318 21258344 23752268 24981860 26186194 26496610 26949739 28514442 details
P66B_HUMANRBBP4_HUMANBioGRID, IntAct, MINT11756549 16738318 24981860 27705803 28514442 details
P66B_HUMANRBBP7_HUMANBioGRID, IntAct, MINT11756549 16738318 24981860 26186194 27705803 28514442 details
P66B_HUMANMBD3_HUMANBioGRID, IntAct, MINT11756549 12183469 16738318 21516116 24981860 25123934 25416956 26186194 26344197 28514442 details
P66B_HUMANLYOX_HUMANmatrixdb25118846 details
P66B_HUMANAAKB2_HUMANBioGRID, IntAct24722188 25416956 details
P66B_HUMANTRI27_HUMANBioGRID, IntAct25416956 details
P66B_HUMANGOGA2_HUMANBioGRID, IntAct25416956 details
P66B_HUMANTRAF1_HUMANBioGRID, IntAct25416956 31515488 details
P66B_HUMANUSBP1_HUMANBioGRID, IntAct25416956 details
P66B_HUMANCACO2_HUMANBioGRID, IntAct25416956 details
P66B_HUMANTEX11_HUMANBioGRID, IntAct25416956 details
P66B_HUMANRPGR1_HUMANBioGRID, IntAct25416956 details
P66B_HUMANCEP70_HUMANBioGRID, IntAct25416956 details
P66B_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details
P66B_HUMANNGB_HUMANBioGRID, IntAct32296183 details
P66B_HUMANSBK3_HUMANBioGRID, IntAct32296183 details
P66B_HUMANCDN2D_HUMANBioGRID, IntAct32296183 details
P66B_HUMANGPSM3_HUMANBioGRID, IntAct32296183 details
P66B_HUMANNDK7_HUMANBioGRID, IntAct32296183 details
P66B_HUMANZGPAT_HUMANBioGRID, IntAct32296183 details
P66B_HUMANFHL2_HUMANBioGRID, IntAct32296183 details
P66B_HUMANNOXA1_HUMANBioGRID, IntAct32296183 details
P66B_HUMANMBD2_HUMANBioGRID, HPRD, IntAct11756549 12183469 16415179 24981860 26186194 26344197 28514442 details
P66B_HUMANZBT7A_HUMANDIP26816381 details
P66B_HUMANH31_HUMANBioGRID, IntAct16415179 26527279 29568061 details
P66B_HUMANH2A2C_HUMANBioGRID16415179 details
P66B_HUMANH2B2E_HUMANBioGRID16415179 details
P66B_HUMANH4_HUMANBioGRID16415179 30804502 details
P66B_HUMANSUMO2_HUMANBioGRID19394292 32786267 details
P66B_HUMANRBPMS_HUMANBioGRID21516116 details
P66B_HUMANERPG3_HUMANBioGRID26030138 31722399 details
P66B_HUMANERCC6_HUMANBioGRID26030138 31722399 details
P66B_HUMANASXL1_HUMANBioGRID32683582 details
P66B_HUMANKAT2B_HUMANHPRD, IntAct16415179 details
P66B_HUMANHDAC2_HUMANBioGRID, IntAct, MINT11756549 21258344 23752268 24981860 26186194 26949739 28514442 30737378 details
P66B_HUMANLOXL1_HUMANmatrixdb25118846 details
P66B_HUMANLOXL3_HUMANmatrixdb25118846 details
P66B_HUMANCHD5_HUMANBioGRID, IntAct24981860 25247294 26186194 28514442 details
P66B_HUMANMTA2_HUMANBioGRID, DIP, IntAct11756549 22939629 24981860 26186194 26344197 26816381 28514442 details
P66B_HUMANZN827_HUMANBioGRID, DIP25150861 details
P66B_HUMANDISC1_HUMANBioGRID, IntAct, MINT29961565 31413325 details
P66B_HUMANMIPT3_HUMANIntAct31413325 details
P66B_HUMANFOXP1_HUMANBioGRID20185820 details
P66B_HUMANFOXP2_HUMANBioGRID20185820 details
P66B_HUMANSOX2_HUMANBioGRID21532573 details
P66B_HUMANZBTB1_HUMANBioGRID24657165 details
P66B_HUMANSIR6_HUMANBioGRID24169447 details